Severe malarial infection.

Severe malarial infection in a patient with sickle-cell anaemia.

Meningococcal Toxæmia Accompanying Malarial Infection

Urticaria Due to Malarial Infection

(1919) regard urticaria as a manifestation of hypersensitivenes's to the malarial parasite as extremely rare. In recent years, cases showing urticaria as a result of hypersensitiveness to malarial parasites have been reported by Eyermann and Strauss (1930), Davies (1936), Gouriou (1938) and Agrama (1940) in Africa and Europe and by Chatterjee (1939) in India, who reported three cases. The case ...

Severe Malarial Anemia: Innate Immunity and Pathogenesis

Greater than 80% of malaria-related mortality occurs in sub-Saharan Africa due to infections with Plasmodium falciparum. The majority of P. falciparum-related mortality occurs in immune-naïve infants and young children, accounting for 18% of all deaths before five years of age. Clinical manifestations of severe falciparum malaria vary according to transmission intensity and typically present as...

Malaria-filaria coinfection in mice makes malarial disease more severe unless filarial infection achieves patency.

Coinfections are common in natural populations, and the literature suggests that helminth coinfection readily affects how the immune system manages malaria. For example, type 1-dependent control of malaria parasitemia might be impaired by the type 2 milieu of preexisting helminth infection. Alternatively, immunomodulatory effects of helminths might affect the likelihood of malarial immunopathol...